Tylenol Extra Strength caplets with 500 mg of acetaminophen help reduce fever and provide temporary relief of minor aches and pains. From a doctor-recommended brand of pain reliever, each caplet contains 500 mg of acetaminophen for effective, extra-strength pain relief. Both a fever reducer and pain reliever, it relieves minor aches and pains due to headache, backache, toothache, minor pain of arthritis, the common cold and premenstrual/menstrual cramps. When used as directed, this extra-strength pain reliever has an excellent safety profile and can be used by adults and children 12 years and older.